Published: June 5, 2024

Naloxone and Naltrexone–What’s the Difference?

Written by QuickMD Publications Team

2 minutes

Naloxone (Narcan)

Naloxone (Narcan) and naltrexone (Vivitrol) both interact with the opioid receptors in the brain and spinal cord, preventing opioids from coming in contact with these receptors. The primary difference between these medications lies in their speed, duration of action, and specific applications.

What is Naloxone (Narcan)?

Naloxone is an emergency medication used to rapidly reverse the effects of opioid overdose. It is designed for situations where patients are found unconscious, barely breathing, with pinpoint pupils, and possibly with blue lips or nose, indicating a lack of oxygen. Naloxone works quickly to restore normal respiration within minutes.

However, its effect tends to last less than an hour, necessitating immediate medical attention and transportation to the hospital for further stabilization.

What is Naltrexone (Vivitrol)?

Naltrexone is a longer-acting medication used primarily to treat opioid use disorder (OUD) and alcohol addiction. Unlike naloxone, naltrexone is not used for emergency overdose situations. Instead, it helps patients maintain abstinence from opioids by blocking the euphoric and sedative effects of the drugs. When patients take naltrexone, they lose their cravings for opioids and can focus on recovery.

Additionally, naltrexone is effective in treating alcohol addiction by blocking the opioid receptors that alcohol activates, thereby reducing the pleasurable effects of alcohol consumption.

Where Can I Get Naltrexone?

QuickMD can prescribe naltrexone via video or phone during a telemedicine appointment. The prescription will be sent electronically to your pharmacy of choice, making it convenient and accessible.

Conclusion: Choosing Between Naloxone and Naltrexone

While both naloxone and naltrexone serve crucial roles in managing opioid-related issues, they are used in different contexts. Naloxone is a life-saving medication for immediate overdose situations, while naltrexone is a long-term treatment option for those seeking to overcome addiction to opioids and alcohol.

Get in Touch 

If you or a loved one needs support in managing opioid or alcohol addiction, contact QuickMD for a telemedicine appointment and explore your treatment options with naltrexone.

Disclaimer

Articles on this website are meant for educational purposes only and are not intended to replace professional medical advice, diagnosis or treatment. Do not delay care because of the content on this site. If you think you are experiencing a medical emergency, please call your doctor immediately or call 911 (if within the United States). This blog and its content are the intellectual property of QuickMD LLC and may not be copied or used without permission.

QuickMD has strict referencing policies and relies on reputable sources, including peer-reviewed research, clinical guidelines, medical organizations, and government and public health agencies, among others. Learn more about how we ensure accuracy in our content by reading our editorial guidelines.

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