As with starting any new medication, it’s common to notice some side effects in the early stages of treatment, and Clonidine is no different. Some people experience drowsiness, dizziness, dry mouth, or fatigue, and in some cases blood pressure may drop lower than usual—especially when standing up quickly. More serious side effects are possible as well, so please read the full prescribing information for complete details. Until you know how Clonidine affects you, it’s safest not to drive, operate heavy machinery, or do activities that require quick reflexes. Avoid drinking alcohol while using Clonidine, since this can increase drowsiness and other side effects. It’s important not to stop taking Clonidine suddenly without talking to your provider, as this can cause a rapid increase in blood pressure. If you have questions or notice symptoms that concern you, your QuickMD provider can guide you on next steps.