

Estradiol vaginal inserts online
Goodbye, dryness! Estradiol vaginal inserts restore moisture and ease irritation, so intimacy and daily life feel more comfortable again.
Targets symptoms right where they start
Low-dose, localized hormone therapy
Prescription access for just $79
Get access with your Menopause Hormone Therapy Membership
Get your first month free!

Medication can only be prescribed after a consultation with a licensed provider, who will recommend the best option if you are eligible. Memberships include a visit with a licensed provider, ongoing support, and related services. Additional charges may apply if a medication is prescribed.
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Perimenopause and menopause symptom relief. No insurance required.
MHT Membership
For $79 a month, you'll have quick access to doctors, prescriptions, and hormone therapy that's designed around your health. Simple, affordable, and always on your terms.
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Getting started with Estradiol vaginal inserts at QuickMD
Description
Estradiol vaginal inserts are a bioidentical prescription medication that work locally to restore estrogen in the vaginal tissues. By delivering estrogen directly where it’s needed, they help relieve dryness, itching, burning, and discomfort during intimacy, while also supporting urinary health and lowering the risk of recurrent UTIs. Because inserts are low-dose and localized, very little is absorbed into the rest of the body, which helps minimize side effects. Estradiol vaginal inserts may also be prescribed for women who do not produce enough estrogen naturally. You can meet with a QuickMD provider to see if estradiol vaginal inserts are the right option for you.
How to use
Use estradiol vaginal inserts only as directed by your QuickMD provider. This medication is for vaginal use only and should not be taken by mouth. Wash your hands before and after inserting. Place one insert into the vagina, using your finger or the applicator provided. Be sure to insert the full dose as prescribed. Staying on schedule helps keep hormone levels steady and symptoms under control. Each prescription comes with a patient information leaflet. Be sure to read it carefully, and ask your provider if you have any questions.
Benefits
- Relief from vaginal dryness, burning, and itching
- Greater comfort during intimacy and sex
- Reduction in pain or irritation with urination
- May help prevent frequent urinary tract infections (UTIs)
- Restores moisture and elasticity to vaginal tissue
- Low-dose, localized treatment with minimal systemic absorption
- Bioidentical estrogen that matches your body’s own
- Small, easy-to-use insert for discreet, targeted relief
Side effects
Serious or adverse side effects from estradiol vaginal inserts are rare. However, some women may experience mild vaginal irritation, itching, discharge, or light spotting, especially when starting treatment. Less commonly, breast tenderness, nausea, or headaches may occur.
This is not a full list of side effects, interactions, or warnings, and it should not replace medical advice. For guidance tailored to your health and medications, always talk with your healthcare provider or pharmacist.
Safety information
Estradiol vaginal inserts must be prescribed by a licensed provider. A consultation with a QuickMD provider is required to review your health and determine if this prescription medication is appropriate for you.
Frequently asked questions
How much does estradiol vaginal inserts cost?
Estradiol vaginal inserts start at $X with QuickMD’s cash-pay option, giving you clear, upfront pricing with no hidden fees. Many women prefer this route because it’s simple, stress-free, and allows their medication to be shipped right to their door. If you’d rather use insurance, your provider can send your prescription to your local pharmacy. Costs and coverage depend on your plan, but your QuickMD provider will walk you through the options so you can choose what works best for your health, your budget, and your life.
How far to insert an estradiol applicator?
The estradiol applicator is typically inserted into the vagina as far as it will comfortably go, usually until the base of the applicator is at the vaginal opening. Once in place, the plunger is pressed to release the medication. Always follow the instructions provided with your prescription and use exactly as directed by your healthcare provider.
Do I need a prescription for estrogen suppositories?
Yes. Estradiol vaginal suppositories (inserts) are prescription medications. A licensed healthcare provider must evaluate your symptoms and determine if this treatment is appropriate for you.
How the membership works
Say yes to your Menopause Hormone Therapy Membership
To begin your MHT Membership, simply book your first visit with a QuickMD doctor who understands perimenopause and menopause. Your first visit is included in your $79 monthly membership, so there’s no added cost to get started. During that appointment, your doctor will take time to learn your health history, listen to your symptoms, and answer your questions. Together, you’ll review treatment options and decide whether hormone therapy feels like the right choice for you. From day one, you’ll have care that’s supportive, personal, and focused on helping you find lasting relief.
Unlock the perks of woman-centered care
Your membership gives you immediate access to answers when you need them most. Each month, your first doctor’s visit is included in your membership, and if you need additional support, extra visits are just $49. If medication could help ease your symptoms, your provider will take the time to discuss your options and prescribe what you need during your visit. You can choose to have it shipped directly to your home with transparent pricing, or sent same-day to your local pharmacy. There are no contracts to lock you in, so you can cancel anytime. It’s flexible care built around what you’re going through, so you get the care you deserve.
Find relief with Estradiol vaginal inserts, if right for you
If your provider determines estradiol vaginal inserts are right for you, they can prescribe them as part of your treatment plan. Each insert delivers a low dose of estrogen directly to the vaginal tissues, helping restore balance and relieve dryness, itching, and discomfort. With regular use, many women notice greater comfort during intimacy, less daily irritation, and improvements in urinary health. Over time, vaginal tissue can regain moisture and elasticity, making everyday life feel more comfortable. With your membership, you’re able to have check in with your doctor to track progress and adjust care as needed.
Get Estradiol vaginal inserts at QuickMD
Available 7 days a week
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