Estradiol vaginal cream online
Here’s to comfort! Estradiol vaginal cream relieves dryness and irritation, so intimacy and daily life feel comfortable again.
Works with your body to restore balance
Localized, topical hormone therapy
Prescription access for just $79
Get access with your Menopause Hormone Therapy Membership
Get your first month free!
Medication can only be prescribed after a consultation with a licensed provider, who will recommend the best option if you are eligible. Memberships include a visit with a licensed provider, ongoing support, and related services. Additional charges may apply if a medication is prescribed.
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Perimenopause and menopause symptom relief. No insurance required.
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Getting started with Estradiol vaginal cream at QuickMD
Description
Estradiol vaginal cream is a bioidentical prescription medication that works locally to restore estrogen in the vaginal tissues. By targeting this area directly, it helps relieve dryness, itching, burning, and discomfort during intimacy, while also supporting urinary health and lowering the risk of recurrent UTIs. Because it’s used in small doses, very little is absorbed into the rest of the body, which keeps side effects minimal. Estradiol vaginal cream may also be prescribed for women who do not produce enough estrogen naturally. You can meet with a QuickMD provider to see if estradiol vaginal cream is the right option for you.
How to use
Use estradiol vaginal cream only as directed by your QuickMD provider. This medication is for vaginal use only and should not be taken by mouth. Wash your hands before and after applying. Use the applicator provided to measure and insert the prescribed amount of cream while lying on your back with knees bent. After each use, wash the applicator with warm, soapy water and rinse well. Staying on schedule helps keep treatment effective and symptoms under control. Each prescription comes with a patient information leaflet. Be sure to read it carefully, and ask your provider if you have any questions.
Benefits
- Relief from vaginal dryness, burning, and itching
- Greater comfort during intimacy and sex
- Reduction in pain or irritation with urination
- May help prevent frequent urinary tract infections (UTIs)
- Restores moisture and elasticity to vaginal tissue
- Low-dose, localized treatment with minimal systemic absorption
- Bioidentical estrogen that matches your body’s own
- Easy-to-use cream with applicator for targeted relief
Side effects
Serious or adverse side effects from estradiol vaginal cream are rare. However, some women may experience mild vaginal irritation, itching, discharge, or spotting. Less commonly, breast tenderness, nausea, or headaches can occur.
This is not a full list of side effects, interactions, or warnings, and it should not replace medical advice. For guidance tailored to your health and medications, always talk with your healthcare provider or pharmacist.
Safety information
Estradiol vaginal cream must be prescribed by a licensed provider. A consultation with a QuickMD provider is required to review your health and determine if this prescription medication is appropriate for you.
Frequently asked questions
How much does estradiol vaginal cream cost?
Estradiol vaginal cream starts at $X with QuickMD’s cash-pay option, giving you clear, upfront pricing with no hidden fees. Many women prefer this route because it’s simple, stress-free, and allows their medication to be shipped right to their door. If you’d rather use insurance, your provider can send your prescription to your local pharmacy. Costs and coverage depend on your plan, but your QuickMD provider will walk you through the options so you can choose what works best for your health, your budget, and your life.
Is estradiol vaginal cream safe?
Yes, estradiol vaginal cream is generally considered safe for most women when used as prescribed. Because it’s applied directly in the vagina, only a very small amount of estrogen is absorbed into the bloodstream compared to pills or patches, which lowers the risk of side effects. Still, it’s important to use the cream under the guidance of your provider, who will review your health history and make sure it’s the right option for you.
What happens when you start taking estradiol?
When you begin using estradiol, your body gradually restores estrogen levels that have declined during perimenopause or menopause. Over the first several weeks, many women notice vaginal dryness and discomfort start to improve. With continued use, intimacy may feel more comfortable, urinary symptoms like urgency or frequent infections may ease, and overall vaginal health often feels better supported. Relief builds gradually as your body adjusts to treatment.
How the membership works
Say yes to your Menopause Hormone Therapy Membership
To begin your MHT Membership, simply book your first visit with a QuickMD doctor who understands perimenopause and menopause. Your first visit is included in your $79 monthly membership, so there’s no added cost to get started. During that appointment, your doctor will take time to learn your health history, listen to your symptoms, and answer your questions. Together, you’ll review treatment options and decide whether hormone therapy feels like the right choice for you. From day one, you’ll have care that’s supportive, personal, and focused on helping you find lasting relief.
Unlock the perks of woman-centered care
Your membership gives you immediate access to answers when you need them most. Each month, your first doctor’s visit is included in your membership, and if you need additional support, extra visits are just $49. If medication could help ease your symptoms, your provider will take the time to discuss your options and prescribe what you need during your visit. You can choose to have it shipped directly to your home with transparent pricing, or sent same-day to your local pharmacy. There are no contracts to lock you in, so you can cancel anytime. It’s flexible care built around what you’re going through, so you get the care you deserve.
Find relief with Estradiol vaginal cream, if right for you
If your provider determines estradiol vaginal cream is right for you, they can prescribe it as part of your treatment plan. The cream delivers estrogen directly to the vaginal tissues, where it helps restore balance and relieve dryness, itching, and discomfort. With regular use, many women notice greater comfort during intimacy, less irritation day to day, and improved urinary health. Over time, the tissue itself becomes healthier, with restored moisture and elasticity. Through your membership, you and your doctor can check in along the way to be sure your treatment is working for you.
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