

Estradiol and norethindrone online
So long, discomfort! Estradiol and norethindrone tablets bring perimenopause and menopause symptom relief while protecting your uterus.
Symptom relief with uterine protection
Trusted oral combination hormone therapy
Prescription access for just $79
Get access with your Menopause Hormone Therapy Membership
Get your first month free!

Medication can only be prescribed after a consultation with a licensed provider, who will recommend the best option if you are eligible. Memberships include a visit with a licensed provider, ongoing support, and related services. Additional charges may apply if a medication is prescribed.
Start hormone therapy
Perimenopause and menopause symptom relief. No insurance required.
MHT Membership
For $79 a month, you'll have quick access to doctors, prescriptions, and hormone therapy that's designed around your health. Simple, affordable, and always on your terms.
Same-day visits with an actual doctor
Get medications delivered directly to you
Get fast answers from our care team
Getting started with Estradiol and norethindrone at QuickMD
Description
Estradiol and norethindrone tablets are a prescription combination medication that pairs estrogen with a progestin. Estradiol helps restore estrogen levels to ease menopause symptoms like hot flashes, night sweats, and vaginal dryness, while also supporting bone, mood, and sleep health. Norethindrone helps protect the uterus by reducing the risk of endometrial hyperplasia. Together, they provide balanced relief and long-term support for women going through perimenopause and menopause. You can meet with a QuickMD provider to see if estradiol and norethindrone tablets are the right option for you.
How to use
Take estradiol and norethindrone tablets exactly as directed by your QuickMD provider. Swallow one tablet by mouth each day with water, at the same time each day. You may take it with food if needed to reduce stomach upset. Do not take more often than prescribed. Staying on schedule helps keep hormone levels steady and treatment effective. Each prescription comes with a patient information leaflet. Be sure to read it carefully, and ask your provider if you have any questions.
Benefits
- Relief from hot flashes and night sweats
- Better sleep and more energy
- Greater comfort with intimacy
- Support for vaginal and urinary health
- Protection for the uterus
- Helps prevent bone loss and osteoporosis
- Simple, once-daily tablet
Side effects
Some women may experience nausea, stomach cramps, bloating, breast tenderness, or headaches when starting estradiol and norethindrone. Changes in bleeding patterns can also occur, such as spotting, lighter or heavier periods, or missed periods. Less commonly, weight changes, mood changes (like anxiety or depression), or vaginal yeast infections may happen.
This is not a full list of side effects, interactions, or warnings, and it should not replace medical advice. For guidance tailored to your health and medications, always talk with your healthcare provider or pharmacist.
Safety information
Estradiol and norethindrone must be prescribed by a licensed provider. A consultation with a QuickMD provider is required to review your health and determine if this prescription medication is appropriate for you.
Frequently asked questions
How much do estradiol and norethindrone tablets cost?
Estradiol and norethindrone tablets start at $X with QuickMD’s cash-pay option, giving you clear, upfront pricing with no hidden fees. Many women prefer this route because it’s simple, stress-free, and allows their medication to be shipped right to their door. If you’d rather use insurance, your provider can send your prescription to your local pharmacy. Costs and coverage depend on your plan, but your QuickMD provider will walk you through the options so you can choose what works best for your health, your budget, and your life.
Do estradiol and norethindrone cause weight gain?
Some women notice small changes in weight or fluid retention when starting estradiol and norethindrone, while others do not. These shifts are usually mild and may improve as your body adjusts. If you’re concerned about weight changes, your QuickMD provider can talk through what’s normal, what to watch for, and ways to support your overall well-being while on treatment.
What is the difference between estradiol and norethindrone?
Estradiol is a form of estrogen, the hormone that helps relieve menopause symptoms like hot flashes, night sweats, and vaginal dryness. Norethindrone is a form of progesterone, which balances estrogen and protects the lining of the uterus. Together, they work as a team to ease symptoms while helping keep your uterus healthy.
How the membership works
Say yes to your Menopause Hormone Therapy Membership
To begin your MHT Membership, simply book your first visit with a QuickMD doctor who understands perimenopause and menopause. Your first visit is included in your $79 monthly membership, so there’s no added cost to get started. During that appointment, your doctor will take time to learn your health history, listen to your symptoms, and answer your questions. Together, you’ll review treatment options and decide whether hormone therapy feels like the right choice for you. From day one, you’ll have care that’s supportive, personal, and focused on helping you find lasting relief.
Unlock the perks of woman-centered care
Your membership gives you immediate access to answers when you need them most. Each month, your first doctor’s visit is included in your membership, and if you need additional support, extra visits are just $49. If medication could help ease your symptoms, your provider will take the time to discuss your options and prescribe what you need during your visit. You can choose to have it shipped directly to your home with transparent pricing, or sent same-day to your local pharmacy. There are no contracts to lock you in, so you can cancel anytime. It’s flexible care built around what you’re going through, so you get the care you deserve.
Find relief with Estradiol and norethindrone, if right for you
If your provider determines estradiol and norethindrone tablets are right for you, they can prescribe them as part of your treatment plan. This combined therapy replaces estrogen to relieve symptoms while adding progestin to protect the uterus. Over time, many women notice fewer hot flashes and night sweats, more restful sleep, and greater comfort during intimacy. The progestin component also lowers the risk of endometrial hyperplasia, offering important long-term protection. With steady care and ongoing check-ins through your membership, you and your doctor can adjust along the way to ensure treatment is working safely and effectively for you.
Get Estradiol and norethindrone at QuickMD
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